International Journal of Clinical and Diagnostic Pathology

International Journal of Clinical and Diagnostic Pathology

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Vol. 3 Issue 1 Part G

2020, Vol. 3 Issue 1, Part GPages: 435-442

Non-neoplastic urothelial lesions and mimickers of malignancy: Take Cognizance - Avoid negligence

Dr. Prithal G, Dr. Smitha B, Dr. Muktha R Pai, Dr. Sandhya I and Dr. Purnima S Rao
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ABSTRACT
Background: The differential diagnosis of urothelial neoplasms also includes several histologic mimics, the importance of which cannot be overemphasized since misdiagnosis could have serious clinical and prognostic implications.
Aims: To study the variety of non-neoplastic lesions of the urothelial tract that could potentially be confused with urothelial neoplasms.
Material and Methods: A retrospective and prospective study of five years duration was done at a tertiary care hospital including 55 cases of non-neoplastic urothelial lesions. Results were analysed using SPSS22.
Results: Out of 43.62% of cases clinically suspicious for malignancy, majority (18.18%) were florid Proliferation of von brunn nests. Out of 56.3% cases clinically non-suspicious for malignancy majority were nonspecific cystitis (12.72%). The nonneoplastic lesions were more common in males (83.3%). The mean age was 45.6 yrs.
Conclusions: Diagnostic awareness of salient histomorphologic features of the benign mimickers of urothelial neoplasms is critical to avoid rendering false positive diagnoses of malignancy.


International Journal of Clinical and Diagnostic Pathology
How to cite this article:
Dr. Prithal G, Dr. Smitha B, Dr. Muktha R Pai, Dr. Sandhya I, Dr. Purnima S Rao. Non-neoplastic urothelial lesions and mimickers of malignancy: Take Cognizance - Avoid negligence. Int J Clin Diagn Pathol 2020;3(1):435-442. DOI: 10.33545/pathol.2020.v3.i1g.207
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